KMID : 1137020100210030199
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Journal of Gynecologic Oncology 2010 Volume.21 No. 3 p.199 ~ p.202
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Primary amelanotic melanoma of the cervix: case report with review of literature
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Duggal Rajan
Srinivasan Radhika
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Abstract
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Primary malignant melanoma of the uterine cervix is a rare neoplasm with poor prognosis. It may be misdiagnosed especially when amelanotic, in which case immunohistochemistry is useful in reaching the diagnosis. We present one such case of a 65-year-old postmenopausal female patient presenting with bleeding per vaginum. Speculum examination revealed an ulcero-proliferative growth involving the cervix. On histopathological examination it was originally suspected to be a poorly differentiated carcinoma or a non-epithelial malignant tumor, but was subsequently correctly diagnosed by immunohistochemical staining with the HMB-45 antibody and S-100 protein.
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KEYWORD
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Aamelanotic melanoma, HMB-45 antibody
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